Bioactive Ceramic Nanoparticles for Tissue Regeneration
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Ceramic biomaterials in nanoscale regime often show unexpected capacity in tissue healing and disease curing. Cells sense the nanotopological substrates to enable adhesive process, and to adopt preferential elongation and migration; also, cellular differentiation into mature cells like osteoblasts and myoblasts is highly dynamic under the nanotopological cues. Design of therapeutic molecules has emerged a promising tool to provide biomimetic matrix cues to cells and tissues; at the same time, delivery of the molecules through nanocarriers is an exciting area to enable targeted functions like anti-inflammation, angiogenesis, and osteogenesis. This talk covers the current cutting-edge approaches on nano-biomaterials developed to provide therapeutically relevant cues to repair and regenerate dental tissues.