Bioactive Nanomaterials for Tissue Regenerative Therapies
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김해원 단국대학교 Damaged and diseased tissues often face challenging issues including vasculature formation and inflammation. Bioactive nanomaterials with therapeutically relevant functions, such as inflammatory regulation, angiogenic stimulation and stem cell homing can restore and accelerate the repair and regenerative process. Here I talk about the therapeutic functions of bioactive nanomaterials, with an emphasis on their dynamic interactions with cells and molecules at the extra-/intra-cellular space. Key strategies are discussed with some relevant in vivo models including skin wound, osteoarthritis, muscle damage and injured nerve. Refs) Kim HW et al. Biomaterials 142, 62 (2017); Adv Science 1700034 (2017); Biomaterials 116,145 (2017); Mater Horizon 4, 772 (2017); Nano Today 14, 84 (2017); Mater Today 18,573 (2015); Adv Funct Mater 25,193 (2015). |